--- title: Agilent Prime LC Applications --- - [Home](https://www.sepscience.com/) - [Blog](https://blog.sepscience.com/) - [日本語](https://www.sepscience.com/japan) - [Chromatography Forum](http://www.chromforum.org/) - [Analytical Training Solutions](https://www.analytical-training-solutions.com) - [Contact Us](https://www.sepscience.com/eclipse-business-media/contact-us/) - [Subscribe for free](https://www.sepscience.com/subscribe/) [![Separation Science](https://learning.sepscience.com/hubfs/Sepscience_Dec2016/images/-resized-strch-SepSci_WebHeader_v3.png)](https://www.sepscience.com/) - [Food](https://www.sepscience.com/food) - [Enviro](https://www.sepscience.com/enviro) - [Pharma](https://www.sepscience.com/pharma) - [Bio Clinical](https://www.sepscience.com/bioclinical) - [LC](https://www.sepscience.com/lc) - [GC](https://www.sepscience.com/gc) - [MS](https://www.sepscience.com/ms) - [Methods & Applications](https://www.sepscience.com/methods-and-applications/) - [Webinars & eSeminars](https://www.sepscience.com/webinars-and-eseminars/) - [Videos & Tutorials](https://www.sepscience.com/videos-and-tutorials/) - [Home](https://www.sepscience.com/) - [Get in Touch with Us](https://www.sepscience.com/) ![1260-Prime-LC-Separation-Science-header-banner.jpg](https://learning.sepscience.com/hs-fs/hubfs/Companies/Agilent/Prime%20LC/1260-Prime-LC-Separation-Science-header-banner.jpg?width=1920&name=1260-Prime-LC-Separation-Science-header-banner.jpg "1260-Prime-LC-Separation-Science-header-banner.jpg") ### Emulation of the Agilent 1200 Series LC for the Analysis of Antihistaminic Drugs ![App4Thumb](https://learning.sepscience.com/hs-fs/hubfs/Companies/Agilent/Prime%20LC/App4Thumb.png?width=100&name=App4Thumb.png)This Application Note describes the separation of a mixture of five antihistaminic drugs. The drug mixture was analyzed first on an Agilent 1200 Series Quaternary LC. The analytical method was then transferred to a 1260 Infinity II Prime LC using Intelligent System Emulation Technology (ISET). [![Read Application Note >](https://no-cache.hubspot.com/cta/default/2322077/f322d8ae-e33f-4443-8382-7bb353784a4a.png)](https://cta-redirect.hubspot.com/cta/redirect/2322077/f322d8ae-e33f-4443-8382-7bb353784a4a) ### Fast Optimization of Solvent Composition Using BlendAssist ![App5Thumb](https://learning.sepscience.com/hs-fs/hubfs/Companies/Agilent/Prime%20LC/App5Thumb.png?width=100&name=App5Thumb.png)The Agilent 1260 Infinity II Flexible Pump with BlendAssist can be used to vary buffer or modifier concentration using ternary or quaternary gradients. This Technical Overview used BlendAssist for two different approaches. [![Read Technical Overview >](https://no-cache.hubspot.com/cta/default/2322077/03732d51-c9df-434f-a099-0c9226617147.png)](https://cta-redirect.hubspot.com/cta/redirect/2322077/03732d51-c9df-434f-a099-0c9226617147)   ### The Agilent 1260 Infinity II Flexible Pump ![App3Thumb](https://learning.sepscience.com/hs-fs/hubfs/Companies/Agilent/Prime%20LC/App3Thumb.png?width=100&name=App3Thumb.png)The precision of retention times of the 1260 Infinity II Flexible Pump was evaluated under demanding conditions and compared to the 1260 Infinity II Binary Pump. In addition, the composition accuracy, delay volume, and flow accuracy of both pumps were also evaluated by running step gradients. [![Read Technical Overview >](https://no-cache.hubspot.com/cta/default/2322077/cbe29e4f-4621-4c4a-aea4-d009a7f751c8.png)](https://cta-redirect.hubspot.com/cta/redirect/2322077/cbe29e4f-4621-4c4a-aea4-d009a7f751c8) ### Emulation of a Waters Alliance LC for the Analysis of Metoclopramide and its Impurities ![Emulation of a Waters Alliance LC for the Analysis of Metoclopramide and its Impurities](https://learning.sepscience.com/hs-fs/hubfs/Companies/Agilent/Prime%20LC/AppNote6_Thumb-1.png?width=100&name=AppNote6_Thumb-1.png)This Application Note shows the straightforward transfer of an analytical method from the Waters Alliance 2695 LC to a 1260 Infinity II Prime LC ISET. [![Read Application Note >](https://no-cache.hubspot.com/cta/default/2322077/b75706c2-4a84-44c9-a64e-8609e26a10fc.png)](https://cta-redirect.hubspot.com/cta/redirect/2322077/b75706c2-4a84-44c9-a64e-8609e26a10fc)  ### Multiresidue Pesticides Analysis in Food Matrices ![App1Thumb](https://learning.sepscience.com/hs-fs/hubfs/Companies/Agilent/Prime%20LC/App1Thumb.png?width=100&name=App1Thumb.png)This study demonstrates robust screening, and sensitive quantitation of 246 pesticide residues and their metabolites in complex food matrices using the Agilent Ultivo Triple Quadrupole LC/MS system. [![Read Study >](https://no-cache.hubspot.com/cta/default/2322077/46551166-c7cf-4389-9b40-e4e387df71ec.png)](https://cta-redirect.hubspot.com/cta/redirect/2322077/46551166-c7cf-4389-9b40-e4e387df71ec)    Analysis of Mycotoxins in Food Matrices ![App2Thumb](https://learning.sepscience.com/hs-fs/hubfs/Companies/Agilent/Prime%20LC/App2Thumb.png?width=100&name=App2Thumb.png)This study shows the accurate quantitation of 12 regulated mycotoxins in commonly regulated foods in using the Agilent Ultivo Triple Quadrupole LC/MS system.  [![Read Study >](https://no-cache.hubspot.com/cta/default/2322077/06a37109-21e5-4eb4-956f-16b0d3a9634a.png)](https://cta-redirect.hubspot.com/cta/redirect/2322077/06a37109-21e5-4eb4-956f-16b0d3a9634a)     [![Return to Prime LC Homepage >>](https://no-cache.hubspot.com/cta/default/2322077/15a3a735-19af-4812-98a1-92bd1de79c34.png)](https://cta-redirect.hubspot.com/cta/redirect/2322077/15a3a735-19af-4812-98a1-92bd1de79c34) Eclipse Business Media Ltd, Regd in England, No. 06513189, Woodview, Bull Lane Industrial Estate, Sudbury, CO10 0FD, United Kingdom, T +44 (0)161 818 7434, [info@sepscience.com](mailto:info@sepscience.com)   Eclipse Business Media Ltd needs the contact information you provide to us to contact you about our products and services. 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