Emulation of the Agilent 1200 Series LC for the Analysis of Antihistaminic Drugs
This Application Note describes the separation of a mixture of five antihistaminic drugs. The drug mixture was analyzed first on an Agilent 1200 Series Quaternary LC. The analytical method was then transferred to a 1260 Infinity II Prime LC using Intelligent System Emulation Technology (ISET).
Fast Optimization of Solvent Composition Using BlendAssist
The Agilent 1260 Infinity II Flexible Pump with BlendAssist can be used to vary buffer or modifier concentration using ternary or quaternary gradients. This Technical Overview used BlendAssist for two different approaches.
The Agilent 1260 Infinity II Flexible Pump
The precision of retention times of the 1260 Infinity II Flexible Pump was evaluated under demanding conditions and compared to the 1260 Infinity II Binary Pump. In addition, the composition accuracy, delay volume, and flow accuracy of both pumps were also evaluated by running step gradients.