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The eBook contains the following applications:

Analysis of USP <467> Residual Solvents
Analysis of residual solvent is a critical application in the pharmaceutical industry. USP 467 specifies a single column analysis with a secondary analysis in the case of detection above concetration limits. With the Agilent 7697A Headspace Sampler and an Agilent Intuvo 9000 GC configured with an inlet splitter, both analyses can be performed with a single system configured with dual columns and dual detectors.


Agilent Intuvo 9000 GC Analyzer for Blood Alcohol Concentration

Determination of blood alcohol concentration (BAC) requires rigorous control. While gas chromatographic systems configured with headspace samplers and flame ionization detection present the most straightforward analysis, the FID does not provide identification of the analytes. Determination and confirmation of BAC can be achieved on a single system with the Agilent Intuvo 9000 GC and Agilent 7697A Headspace Sampler.


Combined Analysis of N-Nitrosodimethylamine (NDMA) and
N-Nitrosodiethylamine (NDEA) using the Agilent 7697A Headspace Sampler, 8890 GC System, and 5977 GC/MSD

This application note describes the use of the Agilent 8890 GC to analyze impurities in sartan products according to a United States Food and Drug Administration (US FDA) method. The workflow also features an Agilent 7697A headspace sampler and a 5977 GC/MSD. Results corresponded to expected detection values.



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