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Discovery of Biomarkers in Breath: Development and Optimisation of a TD–GC×GC–TOF MS Analytical Platform
This study describes the development of an analytical platform based upon TD–GC×GC–TOF MS and shows its application to the collection and analysis of breath samples.
Discovery of Biomarkers in Breath: Efficient Screening with TD–GC–TOF MS
This study describes an analytical system for the rapid identification of potential disease biomarkers in breath, through the use of sampling onto TD tubes, followed by automated preconcentration and GC–TOF MS. Key advantages of the system described are easy‑to-use non-invasive sampling, high sensitivity through the use of trap-based focusing and an inherently sensitive detector, and software tools for improving workflow and automating the comparison of samples.
Discovery of Biomarkers in Breath: Enhancing Separation and Identification using GC×GC–TOF MS
This study describes the comprehensive, high-sensitivity screening of disease biomarkers, through use of sampling onto TD tubes, automated preconcentration, and GC×GC–TOF MS. Key advantages of the system described are enhanced separation of complex breath mixtures (including high-volatility species) using flow-modulated GC×GC, high sensitivity through the use of trap-based focusing and an inherently sensitive detector, and confident identification of the most challenging species with Tandem Ionisation.
Robust Comparison of Terpene Profiles across Cannabis Strains
This study describes the use of GC×GC–FID for robust profiling of terpenes in cannabis. A key feature is the enhanced separation provided by GC×GC, which improves confidence in compound identity and data quality.
Developing a Discovery-based Approach to Cannabis Testing using GC×GC–TOF MS
This poster evaluates a discovery-based approach for terpene profiling using comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry (GC×GC–TOF MS) for enhanced separation and improved sample characterisation. Differences in terpene composition for the same cannabis strain grown under different conditions are investigated using robust flow-modulated GC×GC–TOF MS.
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